Team

Dr. Zhiwen Ye

Dr. Zhiwen Ye (CV)

Junior Principal Investigator

yezhiwen@smart.org.cn

Zhiwen received his Ph.D. in Neuroscience from Imperial College London, where he studied inhibitory circuits of the visual thalamus and sleep–wake regulation with Stephen Brickley, Kenneth Harris, and William Wisden. He then worked as a postdoctoral fellow with Ede Rancz at the Francis Crick Institute, mapping the brain-wide connectivity of visual cortex layer 5 neurons, before joining Nick Steinmetz's lab at the University of Washington as a postdoctoral scholar. There he co-developed ultra-high-density Neuropixels probes (Neuron, 2025) and discovered brain-wide topographically coordinated rotating waves (Science, 2026) by combining widefield imaging with large-scale electrophysiology.

Weiwei Yin

Weiwei Yin

Research Assistant

yinweiwei@smart.org.cn

Weiwei earned his M.Sc. in Neurobiology from the University of Science and Technology of China, where he studied pain–emotion circuits in Prof. Zhi Zhang's lab and published a first-author paper in Anesthesiology on a central amygdala–periaqueductal gray pathway underlying pain in depression-like behavior. As a research assistant in Prof. Zengcai Guo's lab at Tsinghua University, he contributed to projects on basal ganglia control of short-term memory and motor planning, cortical dynamics during sleep–anesthesia transitions, and two-photon imaging of ALS disease models. He brings extensive hands-on experience in mouse stereotaxic surgery, in vivo electrophysiology, wide-field and two-photon calcium imaging, and optogenetic/chemogenetic manipulation.

"Where there is a Wei, there is a pathway — traced spike by spike, mapped frame by frame."
Systems neuroscience | Circuit mapping | In vivo electrophysiology | Wide-field imaging
Focus on large-scale neural activity recording and whole-brain circuit mapping

Bo Wang

Bo Wang

Research Assistant

wangbo@smart.org.cn

Bo earned his M.Sc. in Biology (Biophotonics/Neuroscience) from the Southern University of Science and Technology (SUSTech), working in Prof. Sicong He's biophotonics lab. His research combined in vivo two-photon calcium imaging and two-photon optogenetic stimulation in mouse visual cortex with Python-based analysis of neural population activity — linking neuronal function to single-cell transcriptomic profiles and applying CEBRA to learn low-dimensional neural representations. He is co-first author of a Nature Communications paper on physics-informed deep learning for adaptive optics microscopy.

"I tend to dive deep into whatever genuinely interests me. My interests range from jazz drumming, boxing, and tennis to neuroscience — which, of course, takes the top spot. I'm always curious about how things work, especially the brain."

Sicheng Lai

Sicheng Lai

Visiting Student

sicheng.lai.25@ucl.ac.uk

Sicheng is an undergraduate student in Applied Medical Sciences at University College London (UCL), where she has built strong foundations in human physiology, cellular biology, and data interpretation. She previously worked as an assistant laboratory technician at Harbin Institute of Technology (Shenzhen), conducting microneedle skin-penetration experiments to evaluate a novel biomedical sensor, and completed a research project on liver regeneration at Cornell's Biomedical Science Pre-College Summer Program. She has also explored AI-driven brain tumor MRI segmentation with CNN/U-Net architectures and is experienced in Python-based data analysis.

"I'm fascinated by what becomes possible when biology, data, and technology come together, while my curiosity often draws me to uncover the logic behind how things work. Outside the lab, my interests are just as varied, ranging from hiphop music and diving to volleyball, and I'm always keen to explore something new."

Join Us

The Ye Lab is now recruiting Associate/Assistant Researchers, postdoctoral fellows, research assistants, and visiting students, across areas spanning neuroscience, computation neuroscience, machine learning, and mechanical/electronic/automation engineering. We warmly welcome early-career scholars with strong curiosity and a passion for research to join us.

Please send application materials and reference letters to the lab email address: systemsneuro@smart.org.cn

For more details, please visit: Recruitment in the Ye Lab.